In contrast to our findings with GABRG1 we did not find a GABRA2 haplotype association with AUD in either sample. In a previous analysis in these two populations we had found a complex GABRA2 association with AUD in men only that was mediated by trait anxiety (Enoch et al, 2006a). The observed findings in our current study suggest that the association signal coming from GABRG1 is more robust than that from GABRA2.
