The demographic and smoking history characteristics of genotyped participants from the three clinical trials are shown in Table 1. Patients in the analysis had a mean age of approximately 43 years, and nearly 50% of the population was female. They smoked on average 22 CPD (SD 9.4), and an average score of 5.3 on the Fagerström Test for Nicotine Dependence (SD 2.1) indicated a moderate level of addiction. There were no significant differences in demographic variables or baseline characteristics across the three treatment groups.
