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Chunk #40 — Genome-wide association studies of alcohol dependence — Subset of GWAS and criteria used for generation functional hypotheses

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Genetic studies of alcohol dependence in the context of the addiction cycle.
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dependence are considered; GWAS examining alcohol consumption in non-dependent subjects are excluded.Fourth, priority was given to candidate genes with SNPs in non-intergenic regions of the genome The majority of the SNPs we discuss are found in introns (see Table 3)Fifth, priority was also given to top ranking candidate genes with evidence of multiple different SNPs within the same gene associated with alcohol dependence.