Chunk #8 — RESULTS

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Modelling schizophrenia using human induced pluripotent stem cells.

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Consistent with published reports, Loxapine increased NRG1 expression in neurons21. Loxapine also increased expression of several glutamate receptors. ADCY8, PRKCA, WNT7A and TCF4 also showed ameliorated expression with Loxapine (Fig. 4F; SI Fig. 11E).