vessel disease. CE=cardioembolic stroke.*Statistics shown are after removal of discovery populations showing an association between the gene and stroke from original publications—ie, deCODE excluded for PITX2, ZFHX3;8, 9 WTCCC2-UK and WTCCC-Munich excluded for HDAC9;14 WTCCC2-UK and WTCCC2-Munich, ISGS/SWISS, GEOS, and MGH-GASROS excluded for CDKN2a/CDKN2b (9p21);10 Rotterdam, ARIC, FHS, and CHS excluded for NINJ2.12†One-sided p value.