Chunk #6 — Background — GemErr

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GemSIM: general, error-model based simulator of next-generation sequencing data.

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GemErr generates empirical error models from real data. A SAM format alignment of control data is used as input. A list of polymorphic sites or sites which are known to differ from the reference genome may also be supplied; these sites are then considered to be true SNPs and are ignored during error model calculation.