We used the calculated continuous weighted dimension score of the Brief Symptom Inventory depression subscale with the addition of the additional four items in order to assess the current depression state.40 Recent life stress (RLE) was measured by the List of Threatening Experiences questionnaire41 divided into four validated subscales (Supplementary Table S3), and covering the events occurring in the previous 12 months. The four subscales included intimate relationship problems (RLE-relationship), financial difficulties (RLE-financial), illness/injury (RLE-illness) and social network disturbances (RLE-social).
