Afterwards, we tested if connectedness of DEGs was significantly deviated (one-tailed, larger) from the null hypothesis by simulation. A multiple comparison correction was used to correct p-values [59].Table 1Number of tissues by brain region and developmental stage used in network analyses [64]Number of specimensBrain RegionTissue8–12 pcw13–26 pcw4mon–11Y13–23 YFCDFCDorsolateral prefrontal cortex18383719MFCAnterior (rostral) cingulate (medial prefrontal) cortexOFCOrbital frontal cortexVFCVentrolateral prefrontal cortexSCSTRStriatum13343218MDMediodorsal nucleus of thalamusAMYAmygdaloid complexHIPHippocampusSMA1CPrimary auditory cortex (core)14363219M1CPrimary motor cortex (area M1, area 4)S1CPrimary somatosensory cortex (areas S1,3,1,2)V1CPrimary visual cortex (striate cortex, area V1/17)TPITCInferolateral temporal cortex (area TEv, area 20)10283218STCPosterior (caudal) superior temporal cortex (area TAc)IPCPosteroinferior (ventral) parietal cortex FC frontal cortex, SC sub-cortical, SM sensory-motor, TP temporal-parietal8–12 pcw: embryonic (stage1); 13–26 pcw: fetal (stage2); 4mon–11Y: infancy to childhood (stage3); 13–23Y: adolescence to adulthood (stage4)
