Chunk #21 — Materials and Methods — Follow-up SNP/indel association testing with nicotine dependence in independent samples

Source: Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence.
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UW-TTURC participants were recruited for nicotine dependence and smoking cessation treatment clinical trials in Madison and Milwaukee, Wisconsin beginning in 2001.12 We obtained their Illumina HumanOmni2.5 genotypes, FTND scores and other phenotypic data via dbGaP accession number phs000404.v1.p1. After applying our standard QC procedures (Supplementary Information), there were 1534 UW-TTURC participants included in our study.