to risk factor quantification for those risks supported by the strongest causal evidence such as randomised trials? Or do notions such as the precautionary principle suggest that we should pay attention to risk quantification even for risk-outcome pairs where the evidence is less definitive.70, 71, 72 Because the social response to risks, particularly risks that might be emerging, can take considerable time, ignoring risks for which the evidence is less definitive might actually lead to worse outcomes for society. Conversely, in a world of scarce political and financial resources, devoting attention to risks that might turn out not to be causal might lead to less action on more well documented risks.