N = 180 subjects with bipolar I or II disorder were identified. Of these n = 65 (36.1%) had an additional diagnosis of DSM IV CUD (cannabis dependence and cannabis abuse, CUD in 23 of 77 (29.8%) individuals, in bipolar II subjects and 40.8% (42 of 103 individuals in bipolar I subjects). Any CUDs (dependence and abuse) was found in 36.1% of bipolar I and II individuals.