Genomic DNA was obtained from venous blood samples. Genotyping was performed by Riken Genesis (Yokohama, Japan) using the Illumina HumanOmni1-Quad BeadChip (Illumina, Inc., San Diego). A total of 713,495 autosomal SNPs were assessed for quality using the PLINK v1.07 software [18]. All SNPs with a call rate below 95%, a deviation from Hardy-Weinberg equilibrium at an error level of P<0.001, or a minor allele frequency of less than 10% were excluded. The remaining 534,404 SNPs were used for further analysis. RNA expression and DNA genotype data are available at NCBI’s Gene Expression Omnibus under accession number GSE42488.
