take into account directly whether the linkage signals aggregated have reached genomewide, or “suggestive,” evidence for linkage, themselves. Nonetheless, it is notable that some evidence from the current GSMA does support linkage on chromosome 11 and 17. For example, in the primary 30 cM GSMA of smoking behavior, bin 11.1 (0–29.6 cM) showed nominal significance (PSR= 0.017). Suggestive evidence for linkage has been achieved for bin 17.4 (95–126 cM) which is near the region (20–82 cM) most frequently reported on chromosome 17.
