(Okamoto et al., 2012), further supports the notion that brain ischemia and impaired arterial pulsation could be an exacerbation factor of CAA. Consistent with the experimental data is the clinical finding that arterial stiffness, indicated by pulse wave velocity, has been associated with Aβ deposition in the brains of non-demented elderly adults (Hughes et al., 2013). Therefore, vasoactive drugs could have potential in the improvement of lymphatic congestion and facilitation of Aβ clearance in the brain.
