al., 2011b; Shin et al., 2009; van Tricht et al., 2010); however, none has assessed whether GBRs are abnormal in these patients. GBR abnormalities in CHR patients may reflect vulnerability to the disorder and/or abnormal neurodevelopment, particularly in connection with abnormal function of NMDA and GABAA receptors. A major motivation for identifying neurophysiological abnormalities in a CHR sample is to enhance the accuracy of the prediction of which at risk patients will convert to psychosis, setting the stage for development of targeted preventive interventions aimed at those patients at greatest risk.
