Chunk #24 — Results — Effects of Childhood Disorders on Subsequent Substance Use Disorders — Effects of Childhood Disorders on Outcome within the High Risk Group
Because of the significant colinearity between being a member of a high risk family and having one or more psychiatric disorders of childhood and/or adolescence, it was interest to determine if the predictors identified within the entire sample would also predict SUD outcome within the high risk group. This analysis showed that Conduct Disorder and ADHD were highly significant predictors of later development of SUD, but the presence of MDD or Anxiety Disorders were not (Table 7). The effects of these child/adolescent predictors appear to be similar within the high risk sample and in the larger full sample of high and low risk individuals, but with one exception. MDD had been a significant predictor of outcome in the full sample (Table 4 a, b, c) but was not a significant predictor within the sample of high risk offspring from these multiplex families selected through a female proband.
