Chunk #3 — Introduction

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Polygenic risk scores for smoking: predictors for alcohol and cannabis use?

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yes

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Rietschel and Treutlein (2013) reviewed the current literature on alcohol GWAS and concluded that few genome-wide significant findings have been reported. Among the top-hits are often alcohol dehydrogenase genes (ADH and ALDH2) although a variety of other genes is also reported (28).