The results of linear regression analyses testing for the effects of PER2 rs56013859 genotype, exposure to severe negative life events and the interaction thereof on drinking measures among regular drinkers are presented in Table 2. Analyses revealed a main effect of genotype on the number of drinking days within the past 45 days with G allele carriers consuming alcohol 2.990 (SE = 1.57) days less frequently than A homozygotes. In addition, there was a main effect of severe negative life events on both the total number of drinks used and the AUDIT score, indicating that hazardous alcohol use increased with the number of stressful experiences. Specifically, each additional life event increased the amount of alcohol consumed during the past 45 days by 6.506 (SE = 0.572) drinks and the AUDIT score by 0.572 (SE = 0.112).
