Chunk #28 — Candidate Gene Association Studies for Alcohol and Nicotine Dependence — Other Candidate Genes — Genes Specific for Alcohol or Nicotine Dependence

Source

Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism.

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Likewise, genes involved in nicotine metabolism—for example, genes encoding a family of enzymes known as cytochrome P450—have been suggested to play a role in nicotine dependence and smoking-related behavior (Tyndale 2003). Thus, genes specifically involved in the metabolism of a drug may contribute to vulnerability to dependence on that drug but not on other drugs.