Also, the C-BG-C circuitry appears to be involved in the cognitive aspect of this learning. Dopaminergic innervation of striatum has long been at the center of investigations of the BG role in reward motivated learning, reinforcement and memory. Indeed, there is ample evidence that activity of dopaminergic neurons is related to reward, and dopamine roles in reward and reinforcement-based learning have been studied extensively (Steinberg, Keiflin et al. 2013, Keiflin and Janak 2015). The different models will not be discussed extensively at present, but some aspects of the dopamine roles will be covered.
