Table 1 displays the non-transformed observed values of the descriptive statistics for genotyped participant ages, as well as the primary alcohol use outcomes (drinking index, alcohol abuse and dependence symptom sum, and alcohol abuse or dependence diagnosis), at each assessment stage (IN, FU1, and FU2) by ALDH2 genotype. Model fit comparisons are given in Table 2. For all three outcomes, likelihood ratio tests indicated that including the ALDH2 main effect and the age by ALDH2 interaction effect significantly improved model fit relative to the baseline model. Likewise, the best-fitting model by minimized AIC or QICC included the main effect of ALDH2 as well as the interaction of ALDH2 with age.
