We evaluated the fitted model visually, comparing predicted density from the model versus the empirical distribution ( Figure 7 ). Overall, we find the model fit is adequate, although we do note that there are some deviations from normality (less variance in earlier cycles, overpopular flow-values, assymetry). The empirical models are available from http://ecogenomic.org/acacia. As we have identified clear chip and kit effects, we recommend using the aforementioned models generated from the same combination of chip and kit as to be analysed.