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Chunk #46 — Discussion

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Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder.
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relation to rs1344706 and their imputed p values. If rs1344706 was only weakly or moderately correlated with a true susceptibility variant, we would expect the association signal at that second SNP to be considerably stronger than observed at rs1344706. The absence of such a signal suggests none of these moderately correlated SNPs are likely to be responsible for the signal detected at rs1344706. On this basis, we conclude rs1344706 is the most likely susceptibility variant.