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Chunk #59 — Discussion

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Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking.
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In summary, the results of the present study indicated that binge-like alcohol drinking by P rats produced increased expression of genes involved in transcription, and synaptic transmission and plasticity within two limbic regions that mediate alcohol drinking, and that different mechanisms may be involved in the enhancement of these processes within each region.