Chunk #12 — 3. Methods — 3.1. Statistical Analysis for Single Trait

Source

NCK2 is significantly associated with opiates addiction in African-origin men.

Embedded

yes

Text

Since there are about 20,000 protein coding genes in human genome, we used 0.05/20, 000 = 2.5 × 10−6 as the genome-wide significance threshold for the gene-based association test. In contrast, we used 5.0 × 10−8 as the genome-wide significance threshold for the SNP-based association test [61].