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Chunk #18 — MATERIALS AND METHODS — Genotyping

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A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy.
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The rs1051730 polymorphism was genotyped in subjects from both studies using standard methods, details of which are presented in the Supplementary Material.