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Chunk #56 — 4. Discussion — 4.4. Source activations of P3, Reward Processing, and Risk for Alcoholism

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Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task.
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In this study, CSD topographic analysis yielded three key findings: i) loss condition showed bilateral frontal sources while the gain condition additionally had a prominent midfrontal source; ii) HR offspring (younger males and females as well as older males) displayed weaker CSD sources at the frontal regions in comparison their LR counterparts; and iii) a weaker prefrontal sink activation was found in younger HR offspring compared to the LR group during both loss and gain conditions in males and only during loss condition in females.