sets have been added to WebGestalt. To demonstrate the usefulness of these new gene sets, we uploaded a recently published gene expression signature for colorectal cancer prognosis (24), which includes 487 genes inferred by prioritizing candidate genes identified from genomic and transcriptomic studies on a protein–protein interaction network. The list of all 11 521 genes in the network was used a reference set for the enrichment analysis. As expected, the disease association analysis in WebGestalt correctly identified ‘Colorectal Neoplasms’ as the most enriched disease term (FDR = 7.77e-9). Interestingly, the drug association analysis also correctly identified ‘Fluorouracil’ (FDR = 0.043), a primary drug used in the treatment of colorectal cancer.
