top 33 genes, the median GWAS P-value of the associated cis eQTL SNPs is 0.28, which is much lower than the genome-wide (i.e. for all cis eQTL SNPs) median GWAS P-value of 0.50 and significantly lower than expected for a random set of 33 genes (by permutation, P = 0.006; Fig. 4; Supplementary data, Table S6). When we considered larger window sizes, we found that the most significant enrichment was at 193 genes, with a median GWAS P-value of the associated SNPs of 0.39 (by permutation, P = 8 × 10−4; Fig. 4; Supplementary data, Table S6).
