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Chunk #33 — Discussion

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Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome.
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Examining the effects of CIE exposure on neuroblastoma cells allowed us to measure changes in neurotransmitter systems that cannot be studied in non-neural cell lines. There are limitations, however. The lack of other cell types found in brain could affect their response to ethanol, as could the lack of the spatial differentiation in brain.