Extracted neuroimaging data values were winsorized (to ±3 S.D.s; left VS: n = 9; right VS: n = 9) to maintain variability while limiting the influence of extreme outliers before being analyzed in PASW Statistics (version 19; SPSS Inc.). A regression-based moderation model was tested using the PROCESS macro for SPSS (Hayes, 2013) to examine main and interactive effects of ELS (i.e. CTQ score) and reward-related VS reactivity (i.e. positive reward > negative loss) on anhedonia (i.e. MASQ-SF AD scale score). Based on evidence that anhedonia may predict other depressive symptoms (Gorwood, 2008; Bijttebier et al. 2012) as well as substance use problems (Hatzigiakoumis et al. 2011; Mezquita et al. 2014), we implemented structural equation models (SEM). Using MPlus (v. 7.11), we tested whether the interaction between ELS and reward-related VS reactivity was indirectly associated with non-anhedonic depression symptoms (i.e. MASQ-SF GDD scale score) as well as problematic alcohol use (i.e. AUDIT scores) via anhedonia and substance-related coping behavior (i.e. substance use brief COPE subscale scores; Fig. 1a, b). All interaction predictor variables (i.e. CTQ scores and VS reactivity BOLD
