Alcoholic probands were recruited from alcohol treatment programs through 6 sites (Begleiter et al., 1995; Foroud et al., 2000); institutional review boards at all sites approved the study. The probands and family members were administered the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) (Bucholz et al., 1994; Hesselbrock et al., 1999). Individuals less than 18 years of age were administered an adolescent version. When multiple interviews were available from an individual, data from the SSAGA with the maximum total number of endorsed DSM-IV AD criteria were utilized, and only for individuals who had ever reported consuming alcohol.
