Perhaps most critically, women who reported rVUS and adolescent cannabis use were more likely to also report ever being pregnant. While we did not have information on the outcomes of these individual pregnancies or whether they were unintended and related to rVUS, lack of contraceptive use is associated with 85% chance of pregnancy within a year (43). These findings raise the possibility that adolescent cannabis use may result in substantial risks associated with unintended pregnancy, including effects on maternal and offspring health (44).