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Chunk #32 — Results — Is Increased Nicotine Dependence Associated With Greater Negative Affect and Craving? — Psychophysiology

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A multimodal approach to assessing the impact of nicotine dependence, nicotine abstinence, and craving on negative affect in smokers.
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For postquit COR EMG, we modeled the effects of FTND, as a main effect and as an interaction term with valence, session, and EOT group status, on each of the physiological measures, covarying for baseline COR EMG. Total FTND score interacted with valence in predicting postquit COR EMG scores, F(3, 1095) = 4.59, p < .004, with slopes indicating that those with higher FTND values had larger COR EMG responses to unpleasant slides than did those with lower FTND values, PE = 0.035, SE = 0.014, t(1095) = 2.58, p < .01 (see Figure 1b). However, there was no interaction of FTND score with EOT group status or session for COR EMG. Overall, these findings suggest that increased nicotine dependence is associated with increased COR EMG response to unpleasant stimuli, regardless of nicotine abstinence status.