Chunk #21 — Results

Source

Racial differences in smoking abstinence rates in a multicenter, randomized, open-label trial in the United States.

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population*Minority (N = 172)White (N = 1,512)Total (N = 1,684)p value Age at randomization (mean ± SD)46.3 (±11.33)42.4 (±11.49)42.8 (±11.53)<0.0001 Gender 0.2278 Female110 (64.0%)895 (59.2%)1005 (59.7%) Male62 (36.0%)617 (40.8%)679 (40.3%) Marital status <0.0001 Never married36 (21.1%)211 (14%)247 (14.7%) Married60 (35.1%)894 (59.3%)954 (56.9%) Separated/divorced/widowed72 (42.1%)381 (25.3%)453 (27%) Other3 (1.8%)21 (1.4%)24 (1.4%) Education 0.1747 Less than HS9 (5.3%)63 (4.2%)72 (4.3%) HS or greater162 (94.7%)1,410 (94%)1,572 (94.1%) Other0 (0%)27 (1.8%)27 (1.6%) Age started smoking (mean ± SD)21.5 (±7.14)18.7 (±5.85)19.0 (±6.05)<0.0001 Cigarettes per day at baseline (mean ± SD)19.0 (±9.03)23.6 (±9.84)23.2 (±9.86)<0.0001 Years of regular smoking (mean ± SD)24.8 (±11.42)23.7 (±11.20)23.8 (±11.22)0.2414 Any prior quit attempts 147 (86.5%)1,299 (86.3%)1,446 (86.3%)0.9383 Prior quit attempts (mean ± SD)3.8 (±3.74)3.4 (±3.87)3.4 (±3.86)0.2271 Overall Fagerström score (mean ±SD)5.7 (±1.93)5.8 (±2.16)5.8 (±2.14)0.5157 Fagerström score 0.2341 1–4 (low)46 (27.5%)408 (27.6%)454 (27.6%) 5–6 (med)64 (38.3%)478 (32.4%)542 (33.0%) ≥7 (high57 (34.1%)590 (40%)647 (39.4%) HSQ: major depression 36 (21.6%)296 (20.3%)332 (20.5%)0.7096 HSQ mental composite: month 3–baseline (mean ± SD)1.3 (±7.72)-1.2 (±8.46)-1.1 (±8.43)0.1144 HSQ physical composite: month 3–baseline (mean ± SD)2.1 (±7.31)1.2 (±6.93)1.3 (±6.95)0.5015 Smoking abstinence at month 3 (week 12) 28 (16.3%)389 (25.7%)417 (24.8%)0.0065 Treatment arm 0.0672 Nicotine inhaler50 (29.1%)512 (33.9%)562 (33.3%) Buproprion71 (41.3%)491 (32.5%)562 (33.4%) Nicotine inhaler + bupropion51 (29.7%)509 (33.7%)560 (33.3%)*Study