remyelinating processes.75 This suggests that our observed increase in OLIG2 activity in individuals with AUD may in part lead to dysregulation of myelination in oligodendrocytes. Indeed, alcohol consumption and alcohol use disorder have been found to be associated with white matter degeneration,76,77 but prior to this study, there had not been a direct link between AUD, demyelination, and specific genes such as OLIG2.
