Chunk #22 — METHODS — Statistical Analysis

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Trends in the genetic influences on smoking.

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The values for t are random variables capturing the survival times (the age of onset for regular smoking) for the jth sibling in the ith pair of twins. Thus, the survival function is conditional on this cluster-specific error term wi, and the resulting hazard functions h(tij | wi) are multiplicative frailty models with a baseline hazard λ0(t0).