Chunk #2 — Resting State Functional Connectivity MRI Signal, Brain Networks, and Common Analysis Techniques — Resting State Functional Connectivity MRI (rs-fcMRI) Signal
An important aspect of these correlations is that they appear to be strongest between functionally related regions (Biswal et al. 1995; Lowe et al. 1998; Greicius et al. 2003; Fox et al. 2005; Dosenbach et al. 2007), even when those regions do not possess direct anatomical connections (Vincent et al. 2007). This observation has led to suggestions that the rs-fcMRI signal reflects the statistical history of coactivity between brain regions, and that this signal can therefore inform researchers about functional relationships within the brain (Dosenbach et al. 2007; Fair et al. 2007; Kelly et al. 2009). Consistent with this idea, recent work has demonstrated that visual perceptual learning (Lewis et al. 2009), repetition priming (Stevens et al. 2010) and memory training (Tambini et al. 2010) can modify rs-fcMRI signal between brain regions.
