Chunk #1 — Introduction

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Genetic variation of the growth hormone secretagogue receptor gene is associated with alcohol use disorders identification test scores and smoking.

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attenuate the rewarding properties of alcohol and nicotine (Jerlhag et al. 2009; Jerlhag & Engel 2011). Further studies involving rodents have shown that ghrelin increases alcohol consumption while a GHSR‐1a antagonist decreases alcohol intake, operant self‐administration of alcohol and prevents relapse drinking (Jerlhag et al. 2009; Kaur & Ryabinin 2010; Landgren et al. 2012; Bahi et al. 2013; Suchankova et al. 2013b).