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Chunk #9 — Methods — Data simulation

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A comparison of multivariate genome-wide association methods.
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Secondly, the traits were constructed by adding up the trait-specific effect of the QTL and a residual component. Here, the trait-specific effect of the QTL was assumed to be additive and obtained by multiplying aj with the number of effect (minor) alleles. The residual component was simulated from a multivariate normal distribution with mean zero and with variance-covariance structure: