Chunk #30 — PPARs AND OLIGODENDROCYTES

Source: PPAR agonists as therapeutics for CNS trauma and neurological diseases.
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Collectively, data from these studies suggest that PPARs likely act in concert to promote oligodendrocyte survival and OPC differentiation and may represent a novel molecular target, that, if activated appropriately, could promote oligodendrocyte replacement and remyelination in the injured or diseased CNS.