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Chunk #24 — Results — Changes in gene expression in the ACB-shell

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Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking.
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The ‘synaptic transmission’ category included significant genes listed in ‘regulation of transmission of nerve impulse’ and ‘regulation of synaptic plasticity’ categories. In addition, individual literature searches of the genes that were significantly different between the control and ethanol groups indicated that 8 more genes could be included within the combined category of ‘synaptic transmission-regulation of nerve impulse-synaptic plasticity’ in the ACB-shell (Table 2). Of the 23 named genes that were different between the ethanol and water groups in this combined BP category, 21 had higher expression levels in the ethanol group.