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Chunk #36 — Clinical applications using human iPSC products

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Induced pluripotent stem cell technology: a decade of progress.
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iPSCs. The therapy has resulted in positive results, stopping macular degeneration and improving the vision of the patient. Although the trial was subsequently put on hold due to mutations observed in a second patient’s iPSCs4, it is expected to resume6. In addition, a recent study has demonstrated the feasibility of transplanting human ESC-derived cardiac progenitor cells embedded in a fibrin scaffold to patients with severe heart failure152.