Chunk #10 — Results — Cis-eQTL associations and colocalization analysis

Source

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

Embedded

yes

Text

In light of the strong cis-eQTL effects and colocalization results described above, we decided to focus subsequent analyses on SPI1 as the strongest candidate gene underlying the disease association in myeloid cells.