Results from a variety of tests therefore suggest that the relationship between impairments in action inhibition and addiction-related behaviors run in both causal directions, with poor inhibition predicting heightened propensity to self-administer drugs and with drug experience causing an erosion of inhibitory abilities. What remains unknown, to some extent, is whether subjects differ in the direction or magnitude of drug-induced changes in action inhibition as a function of their baseline competency, as well as whether this relationship holds for all drugs of abuse (the data gathered so far have mostly involved the study of stimulants).
