Bursts and burst rates of APs in a neuron or across a network of neurons is a common feature extracted from data in MEA applications. Bursts have several meanings and functions in neuroscience, e.g., synchronization, information carrier, and motor pattern generation. Single neurons can exhibit bursting, or burst firing, when APs fire at a high frequency for a period of time, followed by a quiet period. Bursts can be triggered by the network activity (environment) or can be intrinsic to the neuron (phenotype of the cell). There are many algorithms to detect the presence of bursts from single neurons (see Samengo et al., 2013; Bakkum et al., 2014 for some methods).
