Chunk #86 — Future Directions: Combining Stress and Alcohol Models and Assessment of Multigenerational Effects and Therapeutics — Therapeutic Strategies
a methyl-rich diet had beneficial effects on pup mortality rates, prenatal growth, and rate of vertebral and digit malformations in mice prenatally exposed to alcohol, though further work is needed to link this diet with gene-specific methylation changes (Downing et al., 2011). Methyl-rich diet supplementation in adulthood has also been shown to alter epigenetic marks associated with GRs in animals exposed to low licking and grooming during the neonatal period (Weaver et al., 2005).
