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Chunk #14 — 2. Methods — 2.3 Analysis

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Age-varying associations between substance use behaviors and depressive symptoms during adolescence and young adulthood.
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Analyses were conducted using time-varying effect modeling, a type of non-parametric spline regression that estimates the associations between predictors and an outcome as continuous functions of time (Hastie and Tibshirani, 1993; Tan et al., 2012). In these analyses, our time metric was age (coded to the nearest month). By using data from all 4 waves of Add Health, our sample comprehensively spanned the age range from 12 to 31.