We also conclude that it is possible to use animal models to study crucial aspects of the neurobiology underlying SB. Though SB cannot be reproduced in animals, suicide endophenotypes, risk alleles and neurochemical findings may be successfully translated from humans to other species. Emerging neuroscience data provide a better understanding of the factors leading to SB, independently of co-occurring psychopathology labeled in the diagnostic manuals. Additional neuropsychological and brain imaging studies, linked to genetic and environmental factors, are necessary to better understand vulnerability to SB, to identify vulnerable patients and to develop more specific therapeutic tools.
