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Chunk #61 — CHRONIC ALCOHOLISM AND NEUROELECTROPHYSIOLOGY — Chronic alcoholism and resting EEG — Target detection (oddball tasks)

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Understanding alcohol use disorders with neuroelectrophysiology.
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The results for N2 component, especially the amplitude, have been equivocal. Porjesz et al. (1987b) observed longer N2 latency but no changes in amplitude in a visual discrimination oddball task conducted on alcoholics. A multimodal study also reported increased N2 latency and P3 latency in an auditory paradigm (Cadaveira et al., 1991). N2 amplitudes in an auditory oddball task were significantly lower for alcohol-dependent individuals when compared to controls (Realmuto et al., 1993; Cristini et al., 2003) but contrary findings of increased N2 amplitude in alcoholics have also been reported (Olbrich et al., 2000).